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ARF PROTEIN COFACTOR
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DeCS
Descriptor
English
:
ADP-Ribosylation Factors
Descriptor
Spanish
:
Factores de Ribosilacion-ADP
Descriptor
Portuguese
:
Fatores de Ribosilação do ADP
Synonyms
English
:
ADP-Ribosylation Factor
ARF Protein Cofactor
ADP Ribosylation Factor
ADP Ribosylation Factors
Tree Number:
D08.811.277.040.330.300.400.100
D12.644.360.525.100
D12.776.157.325.515.100
D12.776.476.525.100
Definition
English
:
MONOMERIC GTP-BINDING PROTEINS
that were initially recognized as allosteric activators of the MONO(ADP-RIBOSE)
TRANSFERASE
of the
CHOLERA TOXIN
catalytic subunit. They are involved in vesicle trafficking and activation of
PHOSPHOLIPASE D
. This enzyme was formerly listed as EC 3.6.1.47
History Note
English
:
2000; use ADP-RIBOSYLATION FACTORS (NM) 1984-1999
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
34414
Unique Identifier:
D020727
Occurrence in VHL
:
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CID-10
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